Wyckoff, New Jersey, June 11th, 2020:Winn Feline Foundation, in a special funding opportunity co-sponsored by Nestlé Purina Petcare and Mars Petcare is calling for proposals that address the effect that dietary phosphorus and calcium to phosphorus ratio have on renal health in cats.Approximately $400,000 is available to fund proposals of sufficient scientific merit, relevance and potential to impact feline health.
Additional research is critically needed to further the understanding of renal health in cats, and to better define potential risks associated with dietary phosphorus and dietary calcium to phosphorus ratio of foods.A recent consensus agreement from experts in veterinary nephrology and nutrition concluded that excess of certain forms of dietary phosphorus can damage kidneys and cause acute or chronic kidney disease, different phosphorus sources can have different physiological effects, and the detrimental effect of phosphorus is inversely related to the calcium to phosphorus ratio.In addition, short-term acute studies indicate that an increase in post-prandial phosphorus and associated regulatory hormones may explain, in part, the mechanism of adverse effects associated with certain forms of dietary phosphorus. Nevertheless, many gaps in scientific knowledge regarding phosphorus and feline kidney health still exist; therefore, there is need for additional investigators and independent centers to participate in filling in these gaps.The overall goal of such research is to provide evidence that will lead to scientific consensus on safe levels and types of dietary phosphorus for feline diets. High priority areas that have been identified and will be given special consideration include investigation of factors that influence phosphorus bioavailability and metabolism including source and form of phosphorus in foods, identification of biomarkers of renal injury (i.e., especially markers that detect early kidney changes before irreversible damage occurs) and identification ofin vitroassays that correlate within vivofunction of phosphorus sources.
"We are thrilled that Mars Petcare and Nestle Purina Petcare have come to us for facilitation of this grant funding relating to this topic of interest that is very much needed in the health and well-being of our feline family members." says Julie Legred, CVT, Winn Feline Foundation Executive Director. "We are excited about this opportunity to be included and look forward to bringing forth new knowledge and understanding in this area."